CONTENTS: Per 100 mL L-isoleucine 0.51 g, L-leucine 1.03 g, L-lysine 0.71 g, L-methionine 0.28 g, L-phenylalanine 0.38 g, L-threonine 0.48 g, L-tryptophan 0.19 g, L-valine 0.62 g, L-arginine 0.49 g, L-histidine 0.43 g, glycine 0.32 g, L-alanine 0.63 g, L-proline 0.43 g, L-serine 0.45 g, acetylcysteine (equiv to L-cysteine) 0.037 g, L-malic acid 0.15 g, glacial acetic acid 0.138 g, Total amino acids 70 g/L, total nitrogen content 10.8 g/L. 287 uc.
INDICATIONS: v Parenteral nutrition supplement in the following conditions: Acute and chronic renal insufficiency, in hemofiltration, peritoneal and hemodialysis; compensation of amino acid losses during and after dialysis or hemofiltration; renal failure following polytrauma, extensive surgery, and sepsis; supplementing a low protein diet in chronic renal failure patients.
DOSAGE: Recommended Daily Dosage: Up to 0.5 g of amino acids/kg body weight/day in acute and chronic renal insufficient patient not treated by dialysis. Up to 1 g of amino acids/kg body weight/day in patient treated by hemodialysis, hemofiltration or peritoneal dialysis. Dosage should be adjusted according to amino acid requirements depending upon age, body weight and condition of patients. Adequate calories should be administered simultaneously either orally or parenterally. The infusion could be given either by peripheral or central route by suitably adjusting the flow rate. Celemin Nephro is available as a sterile, non-pyrogenic, single-dose container that can be administered through peripheral veins or by central venous route using non-pyrogenic IV administration set with aseptic technique.
CONTRAINDICATION: v Disturbances of the amino acid metabolism. Hepatic coma, serious renal disturbances, hypernatremia, hyperkalemia, CHF, hyperhydration, metabolic acidosis. Long-term parenteral use.
SPECIAL PRECAUTION: v Monitor fluid, serum electrolytes, blood sugar levels & acid base balance. Fat should be included in the dietary regimen to avoid essential fatty acid deficiency.
ADVERSE REACTION: v Chest discomfort & palpitation. Nausea, vomiting, chills & fever.
PACKING: v (7% w/v) 500 mL x 1's